Bigfoot, Adam's father, wants to use his fame for a good cause. Protecting a large wildlife reserve in Alaska sounds like the perfect opportunity! When Bigfoot mysteriously disappears without a trace, Adam and his animal friends will brave anything to find him again and save the nature reserve.

After 52 years of solving mysteries, the Scooby gang reunite at Warner Bros. Studios to reminisce about their favorite cases and how they were filmed. But it turns out that the back lot may have its OWN monster problem. Fred, Daphne, Velma, Shaggy, and Scooby-Doo investigate this mystery while celebrating the legacy of the franchise.

In 2100, when humanity has abandoned the earth, a colony of extravagant creatures still thrives in the deepest abyss of the ocean.