Film director Geum Tae-kyung always thinks of films. Even now, his mind is full of cinematic thoughts.

Directed by Jang Kil-soo, the film revolves around a boy and his younger sister, who live in poverty yet in a pure and innocent way. A boy named Nan-na lives with his grandmother in a remote village near the ocean. But when he turns four, his life gets tougher as he has a baby sister Ok-yi and all the affection he received starts going toward the baby. The free spirited boy, who behaved as he liked, now has to take care of his sister, and he has no choice but to start hating her and teasing her. But for Ok-yi, Nan-na is the best in the world.

In the dead of night, a body donated for organ transplants mysteriously disintegrates into ashes. Soon after, five recipients, given a heart, corneas, lungs, liver, and kidneys, begin to develop supernatural powers. A teenage girl gains immense strength, a hipster manipulates electromagnetic waves, a novelist summons powerful gusts, a factory manager can heal others, and a woman discovers a strange, still-unidentified ability. Together, they form a reluctant but heroic team known as "HI-FIVE." But they aren't the only ones transformed. A cult leader who received the donor’s pancreas gains the terrifying power to drain life energy and sets his sights on stealing the abilities of HI-FIVE to achieve godlike domination.