In 1782, King Jeong-jo of Joseon asks detective K to investigate a series of murders related to a case of corruption within the government.

Kang Seong-hee, a famous lawyer, takes up a case wherein he has to defend a man who is the main suspect in his wife's death. However, a formidable public attorney tries to test his mettle in court.

Lee Jang-hwan receives widespread acclaim and media attention after successfully cloning human embryo stem cells. A TV news program PD, Yoon Min-cheol, receives a phone call from an anonymous source who says he has worked with Dr. Lee on the stem cell project. The source blows the whistle on Lee's work, revealing how Lee fabricated research results and engaged in unethical practices.