A pair of women leave their small town and dud boyfriends behind for fun in Madrid.

Something has gone wrong with the landing gear of a plane en route from Madrid to Mexico City. The group of eccentric travelers on the flight, defenseless in the face of danger, indulge in colourful confessionals, while the outlandish crew attempts to find ways to entertain them.

Dani, paraplegic due to an 'accident' shrouded in mystery, lives in a double locked closet, bitter and immersed in memories of his adolescence. Veronica, paralyzed on one side, hides to her mother that she's a lesbian and has a girlfriend. Adolfo, a blind drag queen, aims to start a new life with his boyfriend. Their lives change when Eduardo, Dani's only friend before the accident, reappears.

Eva does everything possible to forget her ex-partner when something happens.

Susana wakes up after 20 years in a coma. Now a 90s teenager in a 21st century woman's body, Susana will have to navigate a world in which nothing is familiar to her and she will have to learn to live in it.