In 1968, in the Ravenside Military Hospital in a military facility in Pennsylvania, the army loses control of an experiment of a lethal bacteriologic weapon that changes the DNA and transforms human beings into zombies. A group of soldiers is sent to the hospital to eliminate the infected staff and interns but private DeLuca steals a test tube with the virus and hides it inside a vacuum flask. He is transformed into a zombie and killed but the vacuum flask falls in the grass. In the present days, a group of patients in the mental institution Ravenside Memorial Hospital finds the vacuum flask and later when one of them opens the vessel, the culture tube drops on the floor of a bathroom contaminating the group and their Dr. Donwynn.

Trevor (Andrew McIntyre) has never had any particular difficulty in meeting beautiful women to spend time with, but his failure to find the perfect female has left him stymied. Shifting from sorority girls to sex fiends and models, Trevor remains uncomfortable with the idea of settling for just any girl. But after hitting it off with spirited punk rocker Janice (Marnie Robinson), he debates setting aside his quest for physical perfection in order to have a meaningful relationship.