Dr. Roger Girard is a rich scientist conducting experiments on head transplantation. His caretaker has a son, Danny, who, although fully grown, has the mind of child. One day an escaped psycho-killer invades Girard's home, killing Danny's father before being gunned down himself. With the maniac dying and Danny deeply unsettled by his father's death, Dr. Girard decides to take the final step and transplant the killer's head onto Danny's body.

John Considine plays the flamboyant Dr. Death, a thousand-year-old magician who has mastered he art of transferring souls from one body to another and thereby manages to perpetuate himself by jumping from one body to the next. Apparently the Doc is a kindred spirit since his blood is a highly-corrosive acid that can strip flesh from bone

A psychic researcher and his assistants investigate a series of murders of beautiful young women.