A director of a low budget movie decides to kill her fellow cast and crew members as they have used her art to become rich and famous.

An island community finds itself under quarantine, facing an evil, through one young woman, which spreads rapidly. Surviving residents must stop the young woman before she reaches the mainland and infects the wider community.

Amber, a mean popular girl who gets electrocuted and dies, is not allowed to enter into heaven unless she helps the least popular girl in school become Prom Queen within a week, but things do not go as planned.

When Gonzo's breakfast cereal tells him that he's the descendant of aliens from another planet, his attempts at extraterrestrial communication get him kidnapped by a secret government agency, prompting the Muppets to spring into action to rescue their friend.