A woman struggles to recover from a brutal attack by setting out on a mission for revenge.

Dito Montiel, a successful author, receives a call from his long-suffering mother, asking him to return home and visit his ailing father. Dito recalls his childhood growing up in a violent neighborhood in Queens, N.Y., with friends Antonio, Giuseppe, Nerf and Mike.

Small-town boy Shawn MacArthur has come to New York City with nothing. Barely earning a living selling counterfeit goods on the streets, his luck changes when scam artist Harvey Boarden sees that he has a natural talent for streetfighting. When Harvey offers Shawn help at making the real cash, the two form an uneasy partnership.

High school student Wendy has an odd relationship with her five friends: They're openly sexual with each other, swapping partners every week. But this is all thrown into turmoil when she meets Sean, a new student in school who has a crush on her. Wendy wants to be with Sean, but doesn't want to disappoint her friends, whom she has known since grade school. When she does decide to leave them, her best friend, Billie, threatens revenge.

Dawn is an active member of her high-school chastity club but, when she meets Tobey, nature takes its course, and the pair answer the call. They suddenly learn she is a living example of the vagina dentata myth, when the encounter takes a grisly turn.