Mobster Ross Blakely is about to get into a difficult spot when his devout sister Samantha comes to him with an unusual request: rescue her daughter Jennifer from the life of drugs and the influence of her drug-dealing boyfriend. Shocked that his once religious niece had gone so astray, he agrees to his sister's request but quickly learns that rescuing Jennifer might be harder than expected.

Jason, a man with no parenting experience, is on an adventure to win the hearts of his fiancé's skeptical kids before they marry. The plan for them to fly to her parent's remote cabin days before she wraps up work quickly falls apart and the adventure turns to a struggle to survive before this new family can start a life together.

The lives of a teenage runaway, a poet, two criminals, and a model railroad enthusiast intertwine through tales of transition and turmoil, set against the backdrop of the opioid epidemic.

Claire Clauster is the glue that holds her chaotic, lovable family together at the holidays. But this year, after planning a special outing for them, they make a crucial mistake and leave her home alone. Fed up and feeling under appreciated, she sets off on an impromptu adventure of her own. As her family scrambles to find her, Claire discovers the unexpected magic of a Christmas gone off-script.