Horizon interviews some experts and looks at the matters which can change our lives in the future, like: climate change, the future of transport, energy production, gene therapy, artificial intelligence, among other things.

In the last month of the space shuttle programme, Kevin Fong is granted extraordinary access to the astronauts and ground crew as they prepare for their final mission. He is in mission control as the astronauts go through their final launch simulation, and he flies with the last shuttle commander as he undertakes his last practice landing flight. Kevin also gains privileged access to the shuttle itself, visiting the launchpad in the company of the astronaut who will guide the final flight from mission control.

Drawing on 45 years of Horizon archive, Dr Kevin Fong presents a documentary showing how the intriguing possibility of life on Mars has fuelled man's quest to visit the Red Planet.