Chronicles the rise and fall of legendary blues singer Billie Holiday, beginning with her traumatic youth. The story depicts her early attempts at a singing career and her eventual rise to stardom, as well as her difficult relationship with Louis McKay, her boyfriend and manager. Casting a shadow over even Holiday's brightest moments is the vocalist's severe drug addiction, which threatens to end both her career and her life.

In 1880, the criminal called The Wolf is responsible for a murderous rampage in France. When the Brisson Bank is robbed in Paris and the employee Michelle is murdered, the wealthy Chevalier Lucio del Gardo is the only chance to save the bank. Chevalier proposes to the owner M. de Brisson to deposit a large amount of gold, but in return he would like to marry his daughter Cecile. However, Cecile is in love with the efficient clerk Lucien Cortier that belongs to the lower classes and refuses the engagement. In order to get rid off the rival, Chevalier uses evidences to incriminate Lucien, manipulating the incompetent Parisian chief of police.

Stefan Radetzky, a Polish pilot and famous concert pianist, is hospitalised in England from injuries sustained while in combat, and having lost his memory. As Radetzky plays the piano in a trance-like state, the story moves back in time to war-torn Warsaw. During an air-raid, Radetzky meets American journalist Carole, and there is a mutual attraction. Following the fall of Poland, Radetzky and Irish pilot, Mike, escape to Rumania and then on to America. Radetzky continues his musical career in America and meets up again with Carole.

An inventor of a deadly weapon to be used against the allies is injured in a crash. Surgeon, Sir James (Sebastian Shaw) saves his life but learns of the inventors plot.