Nellie Bly, a 23 year-old reporter for Joseph Pulitzer, goes undercover in the notorious Blackwell's Island women's insane asylum in order to expose corruption, abuse and murder.

Travis's tight social group of friends and lovers splits apart when his childhood friend, O'Brien becomes severely mentally ill. Now alone, the characters go their separate ways: Travis helps crowd-fund a socialist revolution in Mexico, O'Brien succumbs to mania and becomes a satirical Youtube celebrity, Kate seeks stability in online dating, and Lox embarks on his first indie rock tour. Their lives continue to cross paths and reconnect through the internet.