True story of a charming, popular American who managed to kill his mother and 3 wives before anyone even suspected him.

Joanne Kilbourn, ex-detective turned university lecturer, is still haunted by the unsolved murder of her politician husband,

Ivy and Skyler have started a popular web site and Ivy's health suffers from the stress. Her doctor has her scanned: she only has short time to live and she starts on expensive, illegal, experimental drugs. But is the doctor lying?

Three stories about the world of opioids collide: a drug trafficker arranges a multi-cartel Fentanyl smuggling operation between Canada and the U.S., an architect recovering from an OxyContin addiction tracks down the truth behind her son's involvement with narcotics, and a university professor battles unexpected revelations about his research employer, a drug company with deep government influence bringing a new "non-addictive" painkiller to market.

A washed-up screenwriter, desperately clinging to his fading youth, is forced to confront the realities of fatherhood when his estranged, pregnant teenaged daughter unexpectedly appears on his doorstep, seeking his help.