Manny Pacquiao, widely considered the world's best pound-for-pound fighter, is defending his WBO welterweight championship against "Sugar" Shane Mosley on Saturday at the MGM Grand Garden Arena in Las Vegas. The fight marks Pacquiao's second defense of the 147-pound title he won from Miguel Cotto in 2009. The first came against Josh Clottey in March 2010, after which Pacquiao moved up and beat Antonio Margarito for a vacant super welterweight title last November. That victory made Pacquiao the first boxer to capture world championships in eight different weight classes (from 112 to 154).

On 20 February 2013, Fury fought highly ranked American former cruiserweight world champion Steve Cunningham (25–5, 12 KOs) in his United States debut at Madison Square Garden Theater on 20 April. The bout was an IBF title eliminator to determine the number 2 world ranking, with the winner then needing to fight unbeaten Bulgarian heavyweight Kubrat Pulev for the mandatory position for a shot at the long reigning world champion Wladimir Klitschko.

Philadelphia’s unified 122-pound world champion Stephen Fulton Jr. battles Los Angeles’ Danny Roman in a matchup between two of boxing’s most consistently explosive fighters. Plus, the delayed broadcast of five-time world champion Gervonta “Tank” Davis defending his WBA lightweight title against No. 1 ranked contender Rolando “Rollie” Romero at Barclays Center in Brooklyn.