Vittorio, an American novelist teaching in Rome, meets the beautiful but damaged Bianca and they rapidly fall into an urgent, tempestuous affair. He's hesitant over their relationship since she seems to thrive on conflict and is constantly baiting him into physical altercation. Bianca gives Vittorio an exquisite leather belt as a gift; he knows immediately that she wants him to whip her with it. Driven by his craving for her, Vittorio complies to Bianca's desire. Their relationship escalates into a dark realm of S&M which becomes more and more self-destructive.

Alfredo is a crude Roman motorcycle repairman who is a friend of Count Max, a gentleman and ex-pleasure lover. The latter invites Alfredo to his residence in Campo dei Fiori and teaches him etiquette, French and how to play poker. The laughter will begin when Alfredo meets and chases the beautiful model Isabell Bellissima in Paris.

A crazed scientist sends out his mutant creations to kidnap young, beautiful men and women to bring back to his lab so he can transplant their brains into the bodies of old, wealthy people.