W817 is back. In the film, we discover that the old friends lost track of each other after their studies. They each followed their dreams and passions and are at a tipping point in their lives. One day, they receive a mysterious video message from tech-geek Carlo. He invites his old roommates to his wedding. During an eventful weekend, Steve, Birgit, Zoë, Tom and Jasmine discover that a lot, and at the same time little, has changed in all these years. But where is Akke? And what is Carlo really up to?

The once unconditional friendship between police officers Vincke and Verstuyft hits a very rough patch when they come up against a series of gruesome murders. Complicating matters even further, a survivor of the killer drives a wedge between them when Verstuyft falls for her charms. Meanwhile, the serial killer has a new victim in sight...