A group of messenger spirits led by Aniceto, including doctor André Luiz, are tasked with going to Earth to help rescue three proteges whose interconnected stories are about to fail.

In Rio de Janeiro, the forty and something years old Mercedes (Lília Cabral) goes to the psychoanalyst and tells the story of her life since she was a girl and lost her mother. Along the three years of analysis, her life changes and she divorces from her husband Gustavo (José Mayer) and has love affairs with the younger Theo (Reynaldo Gianecchini)

"No one loves anyone for more than two years" is an adaptation of Nelson Rodrigues' work about five couples that live in Brazil in the early 60's, who are seen by the society as conventional people, but whose intimate lives turn out to be morally questionable.