A man and wife are terrorized by Mad Scientist Dr. Callistratus who was executed but has returned to life with a heart transplant. Along with his crippled assistant Carl, the 'anemic' Mad Scientist, believed to be a vampire, conducts blood deficiency research on the inmates of a prison hospital for the criminally insane to sustain his return to life.

Scotland Yard is called in when the effigy used in a Guy Fawkes Day celebration turns out to be the burned corpse of a real man.

The wife of a condemned man tries to save him in England by finding the real killer.

A wealthy young layabout tries to double cross the master-crook who has engaged him to do a job.