Armando Pulido, a construction master, simple, good-hearted, hard-working, industrious, and a good friend, tired of the serious economic crisis in Colombia, decides to go to New York in search of the so-called "American dream".

At the age of 17, Griselda Blanco, made her way to the U.S. with a fake passport with her first husband Carlos. Living in Queens with her three sons, Griselda became enticed by the money the drug world offered, and quickly became embroiled with local drug runners. Griselda masterminded the use of beautiful women, the elderly and children as the mules and created false-bottom suitcases to smuggle cocaine from Colombia.

The paths of a couple who'd dated for more than a decade diverge when Juan decides he wants to raise a family and Elizabeth focuses on her career.

In a comedy set during the Christmas novena of a company, Piquiña, an ugly and boastful man, tries to conquer Liliana, the woman desired by all. Convinced of his charm, he goes after her, but Liliana rejects him with a blunt phrase: she would only be with him if he were the last man on Earth.