Construction worker Doug Kinney finds that the pressures of his working life, combined with his duties to his wife Laura and daughter Jennifer leaves him with little time for himself. However, he is approached by geneticist Dr. Owen Leeds, who offers Doug a rather unusual solution to his problems: cloning.

Countless wiseguy films are spoofed in this film that centers on the neuroses and angst of a powerful Mafia racketeer who suffers from panic attacks. When Paul Vitti needs help dealing with his role in the "family," unlucky shrink Dr. Ben Sobel is given just days to resolve Vitti's emotional crisis and turn him into a happy, well-adjusted gangster.

The gang that created Airplane! and The Naked Gun sets its sights on Top Gun in this spoof. Topper Harley is a talented but unstable fighter pilot with an axe to grind: clearing the family name. His mission is to avenge his father and save a mission sabotaged by greedy weapons manufacturers. He also gets involved in a relationship with Ramada Thompson, a woman with an unusually talented stomach. Hot Shots! makes fun of a variety of other films, from Dances with Wolves to The Fabulous Baker Boys.

Topper Harley is found to be working as an odd-job-man in a monastery. The CIA want him to lead a rescue mission into Iraq, to rescue the last rescue team, who went in to rescue the last rescue team—who went in to rescue hostages left behind after Desert Storm.

Failed writer Ray Wyatt is ready to take his own life when a notorious serial murderer steals his latest movie script and begins publicizing it. Revived by the sudden deluge of celebrity, Ray starts tracking the killer to recover the manuscript.

A female bicycle messenger is looking for love in New York City and becomes involved with two very different men.

In the world of the Murkworks where nightmares are made, the evil Synonamess Botch hatches a scheme to make non-stop nightmares. Only Ralph and Mumford, misfits from the cheery land of Frivoli where good dreams are made, can stop him.

Billy Wyatt, a former high school and minor-league baseball player, receives a telephone call from his mother revealing that his former child-sitter, and later in his teens, his first love, Katie Chandler, has died. Wyatt returns home to deal with this tragedy, reminiscing over his childhood growing up with his father, Katie, and best friend Alan Appleby.