The film chronicles the rise and fall of the world's most feared drug lord Pablo Escobar and his volatile love affair with Colombia's most famous journalist Virginia Vallejo throughout a reign of terror that tore a country apart.

A portrayal of Pope Francis of the Catholic Church and the story expressing reasons and events that led to the rise of his popularity and power. His rise to power and radical views would stir controversy as he makes his rise in the world's oldest and largest religious institutions.