Jack Sadelstein, a successful advertising executive in Los Angeles with a beautiful wife and kids, dreads one event each year: the Thanksgiving visit of his twin sister Jill. Jill's neediness and passive-aggressiveness is maddening to Jack, turning his normally tranquil life upside down.

An innocent college couple unknowingly become involved in their Professor's illicit research into the manipulation of love and his recreation of the elusive "Cupid's Arrow".

Peter Highman must scramble across the US in five days to be present for the birth of his first child. He gets off to a bad start when his wallet and luggage are stolen, and put on the 'no-fly' list. Peter embarks on a terrifying journey when he accepts a ride from an actor.