Mobster Ross Blakely is about to get into a difficult spot when his devout sister Samantha comes to him with an unusual request: rescue her daughter Jennifer from the life of drugs and the influence of her drug-dealing boyfriend. Shocked that his once religious niece had gone so astray, he agrees to his sister's request but quickly learns that rescuing Jennifer might be harder than expected.

Army vet Frank Mason has dementia and his son signs him up for a clinical trial of the military's latest drug for mental acuity in combat. But, no one can fathom the drug's side effect--turning people in to homicidal maniacs.