A mad scientist by the name of Dr. Nueve is responsible for unleashing werewolves and a zombie upon the citizens of Stayville, while a local police officer named Karen also a werewolf has been killing off citizens left and right. Intrepid heroes come to the rescue of this city tormented by killer monsters who must be annihilated.

A mysterious technology has transformed the residents of Austin, TX into flesh-craving zombies. Armed with a knife, an axe, and many pairs of flip-flops, middleschooler Dannie and her pee-wee zombie squad take to the streets to battle undead parents, teens, and even a toddler.