Near the end of the 19th century, Prof. John Mayer and his assistant, the scientist Dr. Isabel Reed, accidentally invent a powerful ray. An alien travels to Earth to destroy the machine since it would be a threat to the universe. He initially possesses the mind of Thomas, a sex maniac and serial killer, to get close to Mayer during the demonstration of the machine to scientists and the military. Mayer's niece, Laura, meets an acquaintance of her uncle, the chemist Dr. Paul Rosten, and Mayer invites him to join the research. When Thomas gets close to Mayer, the alien also possesses his mind in order to destroy the device and his notes. Meanwhile, Thomas is not able to control his murderous impulses and attacks several women with a straight razor.

A pair of spies disguised as tourists are stalked by mysterious figures in Mexico's most attractive locations.

Blue Demon returns in one of his best adventures like Agent Zero, who this time is facing a criminal organization that attempts to poison the world with a deadly gas (whose formula is unknown). This time, Zero (Blue Demon) is the only one qualified to investigate and prevent Hans plans, the evil leader of the organization.

A rumor reaches a small town, San Garabato, that a government infiltrator will arrive to check the conditions of the community. Quickly, the municipal president, Don Perpetuo del Rosal, orders the imprisonment of those who might give a bad image. An indigenous man named Calzonzin arrives in town, pursued by two men. He is quickly taken as the infiltrated inspector, and protected by all the local authorities.

Small-time crook teams up with a street urchin for mutual support on the margins of society.

Relatives of a recently deceased man meet at his eerie castle for a reading of the will. They encounter a sinister piano player who turns out to be a toy maker, and his toys are imbued with murderous intentions.

El Topo decides to confront warrior Masters on a trans-formative desert journey he begins with his 6 year old son, who must bury his childhood totems to become a man.