An 11-year-old street boy, Obdulio, who sells newspapers for a living but cannot read or write, finds a magical "Maestro" in the night watchman of the newspaper's office. Obdulio's charismatic mentor not only introduces him to the world of literacy but also teaches him the real meaning of life through the lyrics of the "Murgas" [Carnival Pierrots] during the magical nights of the irreverent and provocative Uruguayan Carnival.

In 1884, the famous painter Juan Manuel Blanes, from Uruguay, is asked to create a portrait of José Artigas. There is only one drawing of his face, done in his old age so Blanes must imagine what he looked like by reading up on his ideas and learning about his life.

Gastón (Jorge Temponi) is very attached to technology and is still in love with an ex-girlfriend who left him. He inherits an old house from his grandfather far from the city and must travel there accompanied by Américo (Carlos Frasca), a clerk somewhat depressed by his old age. The driver and owner of the truck in which they travel is Beto (Jorge Esmoris), a carrier with a somewhat murky past. The place where they are going was visited by the English naturalist Charles Darwin in 1833, where he collected fundamental information to later develop the theory of evolution.

Nalu lives with Ruben, her father, in a small country town near the Brazilian border with Uruguay. When Ruben realizes that his daughter is becoming a woman, an ambiguous closeness begins to develop between them.

The vicissitudes of a musician fresh from prison that seeks to resume playing music with his band, the Chevrolés, whose members are scattered around the city, earning a living wage through various activities.

The future has arrived. Below, in the tunnels, inhabit the "underground": a tribe that survives on the fringes. Above, amidst decay and smog, a corrupt society is ravaged by a religious cult that kidnaps and murders beautiful teenage models. Detective Gutiérrez, tormented in dreams by the image of a young woman whom he has never met, is hired by a wealthy family to find a missing model. Tangled between these two worlds, Gutiérrez will have to push himself to his breaking point to solve the enigma.