After a deadly sickness breaks out in their colony, a group of determined teens set out to retrieve a cure, only to find that the enemy is much closer than they think.

Today has not started well for Ryan. Unwillingly befriended by the weird new kid, he has made himself an enemy of the bloodthirsty football captain, and recklessly promised the girl of his dreams he will throw the party to end all parties. Derailed at every turn by the eccentric vice principal and strange security guard, Ryan's only hope to pull the party together, get the girl, and avoid the footballers is to win over the most unpopular kids at school... one by one.