Young man, Pancho's father wants Pancho to take over his pizzarea, but Pancho prefers telling jokes.

Two guys find a beautiful young woman to take the place of their missing roommate. Everything seems fine until a horrible mistake on drunken night leads all three on a downward spiral.

Andy Stitzer has a pleasant life with a nice apartment and a job stamping invoices at an electronics store. But at age 40, there's one thing Andy hasn't done, and it's really bothering his sex-obsessed male co-workers: Andy is still a virgin. Determined to help Andy get laid, the guys make it their mission to de-virginize him. But it all seems hopeless until Andy meets small business owner Trish, a single mom.

Claire, a charming alcoholic, shows up to her mom's "birthday party" only to find herself the guest of honor at her own intervention.