At 30, Doris can feel her biological clock ticking. For her, nothing can be worse than growing old, lonely and dying a virgin. She needs a man, and she needs one pronto! So to make her dream of walking down the aisle come true, she enlists the help of her best pal, Randy. Will Doris end up with the gorgeous Fil-Am bartender Hans , the intellectual Sean , or the zero self-esteem officemate Inaki? Or will she accept the fact that she’s destined to be single forever, and can be happy that way?

Jennylyn Mercado, Jodi Sta. Maria, Agot Isidro, Coco Martin, and Jon Avila portray five graduating nursing students who are at a crossroads in their lives and their careers. Their different stories are a cross-section of society's nurses. Each character reflects the Pinoy's aspirations, motives, realities, ambivalence, and fears in becoming a nurse.

Hospital worker Conan is hopelessly in love with a sexy and beautiful nurse named Ellen. He is on friendly terms with the alluring lady, but gets desperate when he sees her kissing a resident doctor. The jealous guy seeks the help of his friends and learns about the power of a wish whispered to the dead. He scampers off to a wake and surreptitiously opens the casket. In a barely audible way, he whispers: Mahalin ako ni Ellen.

Little Opao and Biboy grew up together in an orphanage in Taal, Batangas and promised themselves to be best friends forever. As they grow older they head into separate ways; to be adopted by their respective new parents. Opao is adopted by a spinster whose failed career in acting prompts her to mould Opao into a superstar with the nickname Darling. Meanwhile, Biboy is adopted by Crisp Pops.

A motley gang of characters that includes a movie star, a reporter, a congressman, a hairdresser, a jilted, suicidal lesbian and a gold-digging playgirl all end up in the same seedy motel on one very strange night.

Mae and Bogs' long-time friendship gets tested when Bogs gets dumped by his girlfriend and Mae finally admits she's in love with him. The two get into a relationship, but Mae fears this is only Bogs' way of dealing with his previous heartache.

Angelo dreams of creating a medicine that could cure his father’s illness. With some knowledge about medicinal herbs, he makes a living as a faith healer. Everyone believes him, except Cielo Delos Santos, a doctor who swears to do everything to uncover Angelo’s secret. Things get a little complicated when Angelito, an exiled angel comes down to earth to help Angelo become a better man. As the three of them try to achieve their own goals, they realize that they need each other more than they are willing to admit.

A few months after Ina left the position as the President of the Philippines, she is back in the media limelight as she releases a book of her life in her journey as a mother to her children and as a mother to the people of the Philippines. Ina now lives a simple life with her beloved children, together with her long-time best friend, Rowena.

Benedicto "Ben" Caballero is an environmentalist who disapproves of deforestation for villages in mountainous regions in the country.He is more concerned of the environment than that of getting along with his siblings.It is revealed that he was a former lawyer and that he quit because of a matter between right or wrong,and not about winning or losing.He focuses on nature-for him,it's all about saving the planet.

A tribute to filmmakers and National Artists Lino Brocka and Ishmael Bernal. In the "Day" segment, Piolo Pacual portrays the role of William, a drug addict who tries to rebuild his sense of self and reconnect with the people around him. For the "Night" segment, Pascual portrays the role of Philip, who works as a bodyguard for a mayor's son. The bodyguard believes that his boss considers him as part of the family but after a shooting incident, he realizes his real worth to his boss. As he struggles to hide, he is slowly consumed by the claws of darkness lurking the city.