Before introverted word-nerd Zoe gains the courage to enter the National Scrabble Championship, she meets her emotional match in Marty, an irascible recluse. She finds him equally pitted against the opposing forces in her life - other people - including family, co-workers and a couple of particularly irksome adversaries standing in the way of her dream to become the world's second female National Scrabble Champion.

Tom, an overweight young man, takes refuge at his grandmother's cabin in rural Illinois in an attempt to bury the years of being bullied and feeling rejected. While in town, he meets a precocious blind girl named Lilly, who shows him how to be accepted and loved.

Recent college graduates joyride in a stolen cop car only to uncover a secret that will doom mankind.