Tom's Sacrifice is a silent Western.

Grace, daughter of Jim Williams, a ranch owner, and Tom Martin, a Texas ranger, love one another. Buck Miller is the disappointed rival in love. Buck swears vengeance and plans with Delgado, a Mexican outlaw, to capture Grace and her father and hold them for Grace makes her escape and tells Tom and his pals of the outlaws' action.

Tom Merry, a stagecoach driver, is in love with Vicky, daughter of Henderson, superintendent of the Eagle Mining Company. Henderson does not approve of his daughter's choice. Jordan, who works in the office, proposes to Vicky, is refused and when Jordan becomes insulting, Henderson discharges him. Jordan incites the men to a riot at the mining company's office and plans with two others, to hold up the stage which Tom drives, on his return trip and get the payroll.

When Tommy, an Eastern young man, arrives in a Western town, the cowboys see that he is a tenderfoot and make him dance to the tune of a gun. Beecher, a ranchman, Hazel, his daughter, and Sid, the foreman, who is in love with Hazel, rescue Tommy.

Tom is working on a ranch where things have been pretty quiet lately. But today the foreman has received a letter from an old friend, who is sending his daughter to the ranch to get some 'local color' for a story that she is writing. The foreman and the ranch hands decide to stage some events that will give her more excitement than she bargained for.

Bill Herrick, owner of "Run Down" ranch, finds the land is worthless and arranges to sell it at public auction.