In the mid-fifties, El Nini lives in the poorest and most forgotten rural Castile (Spain). He is a child with no more knowledge than those provided by nature. El Nini lives with his father in a cave, and with him he devotes himself to the hunting of water rats, the only means of subsistence they know. But when they are tried to deprive them of their roof and their livelihood, violence will erupt uncontrollably.

A newlywed couple goes to the beach on their wedding day to celebrate those moments that should be the happiest of their lives. But the scariest of nights awaits them, and the wedding...was just the beginning.

Pedro Martín, a young and ambitious doctor, is studying the effect of cancerous cells on mice, but he has run out of mice in his laboratory, since they do not breed there, and he has no funds to purchase more of these expensive laboratory animals from the United States. Nevertheless, his assistant, Amador, informs him that he gave some of the mice to an old trapper, nicknamed “el Muecas”, who lives in precarious conditions in a shanty town outside Madrid, and that this poor man has successfully bred them with the help of the natural heat of his daughters. The incredulous scientist goes to the shanty town to obtain the mice. There, Pedro meets Muecas, Muecas's wife Ricarda and their two daughters Florita and Conchi. With the warmth of the women’s breasts, as the flirtatious Florita shows Pedro, the mice are able to reproduce.

In the near future, the areas between major cities are lawless wastelands. Atolladero is a town run with an iron fist by a corrupt tyrant named The Judge and his murderous enforcer, Madden. One decent cop decides to leave town, but the powers that be don't want that and go after him.

An amateur detective helps a hotel owner to find her younger sister.

Spain, 1977. The first general elections are about to take place after the long dictatorship and the progressive environment of Madrid is easily palpable. Protagonists, Carmen and Juan were once married and now living separately, both have a child. It's one of the only reasons they maintain cordial to one another. Their separation, the political context and the contradictions of the progressives of the time will not defeat the affinity between the two.

Marisa, a 38 years old woman, tells a stranges story to her daughter while they're walking through a level crossing in Madrid. An anthropologist, Jaime, is chased by a mysterious jeep. In the course of the chase, he takes shelter in a small motel. When he settles down, he keeps writing in his personal diary, reflecting his impressions about his work in it.

Three old schoolmates, who in their time as students had formed a kind of secret society called The Black Hand, in order to embitter teachers' lives, meet again years later with very different lives. One is a dad's son who is distracted as best he can; another has become a writer of espionage novels and is persecuted by the CIA, and the third leads an indolent life without further ado. The reunion of the three friends will make the society of La Mano Negra revive.