The pain, the weakness, the silence, the despair. These are some of the feelings faced by a couple lost in drugs. Nights can be seen as the story of people who made mistakes in life, but who still continue to seek happiness. It is about the despair of hopeless lives. The characters are, from the beginning, thrown into an empty and sterile world of indifference. In this true no-man's-land, João and Teresa are confronted with their precarious existence. They are broken pillars of a love that has become silent and painful, they share everything: the house, the drugs, the emptiness and the deprivations of their lives. To make the situation even more dramatic, Teresa falls ill. João does everything to help her, betting on his love for her. He, too, an addict, knows how to ease the pain of his beloved. But unfortunately this help also requires extra money, which forces João to prostitute himself, accelerating his process of destruction and his path to a tragic end.

Francisco just got out of prison after a six year sentence and is now a free man. He wants to change, and after a few days sleeping in the subway tunnels, and some small jobs, he finally gets a room on a cheap hotel. He changes his looks, gets a job, lives his life.