After a 20 year absence, drifter George Walker returns home to settle his grandmother's estate. As if awakening from a long dream, he finds his childhood home condemned and littered with the remnants of squatters. In the midst of trying to save his past, George falls and strikes his head, triggering an onslaught of vivid nightmares and waking visions. As the horror intrudes on George's reality, his conviction grows that someone or something is trying to kill him.

After a comet disrupts the rain cycle of Earth, the planet has become a desolate, barren desert by the year 2033. With resources scarce, Kesslee, head of the powerful and evil Water & Power Corporation, the de facto government, has taken control of the water supply. Unwilling to cower under Kesslee's tyrannical rule, a pair of outlaws known as Tank Girl and Jet Girl rise up, joining the mysterious rebel Rippers to destroy the corrupt system.

The sweet and perky Barbara, the sunny Janis, and the responsible Sandra are a trio of young and attractive nurses who work in the psych ward at a hospital. The threesome really have their hands full dealing with nutty patients, creepy stalkers, and black revolutionaries