Nikos, Christine, Homer, George, Regina, Dimitris, Jim, Margaret, Elias, Monika and Haris return from their summer holidays.

Andreas, an Art History Professor at the Athens School of Fine Arts, is involved both with a sexy intellectual French-Greek woman and a young student of his despite being in love with his beautiful wife. When he finds out he has leukemia and only a few months to live, he decides to keep it a secret but also to talk to the women in his life about his infidelity.

Rival Chicago reporters Sabrina Peterson and Peter Brackett join forces to uncover a train wreck conspiracy.