The UN General Assembly regards antibiotic-resistance as a "global and most urgent threat". The WHO alarms that we could fall back into a "post-antibiotic age". The film tells us how we got there: It is a story about how negligence, greed, and short-sightedness have rendered the lifesaving effects of antibiotics powerless. It is a science-thriller about disillusioned, fighting doctors, rebellious scientists, patients wrestling with life-threatening diseases and diplomats searching for a global solution. They all are Resistance Fighters.

Rose, a stranded showgirl, participates in a local amateur show and wins the prize. After the performance, she meets a wealthy young man who buys her supper, gets her accommodation on a farm adjoining his father's estate, and turns farmhand to win her love.

In pre-revolutionary war days, Daniel Boone captures the white renegade Simon Gerty but lets him go. After Boone moves from North Carolina to homestead in Kentucky, Gerty reappears. This time Gerty kills the Chief's son saying it was a white man and this sends the Indians on the warpath.

A saga centered on the Tierneys, a multi-generational family of New York City Police officers. The family's moral codes are tested when Ray Tierney investigates a case that reveals an incendiary police corruption scandal involving his own brother-in-law. For Ray, the truth is revelatory, a Pandora's Box that threatens to upend not only the Tierney legacy but the entire NYPD.