It is 1967, and Larry Gopnik, a physics professor at a quiet Midwestern university, has just been informed by his wife Judith that she is leaving him. She has fallen in love with one of his more pompous acquaintances Sy Ableman.

Baron, an imprisoned man, strikes up a friendship with cellmate Otis. As the pair hatch an escape plan together, Baron recalls the story of how he met Marmalade, the love of his life, and their Bonnie and Clyde scheme to rob a bank in order to care for his sick mother and give the couple the life they’ve always dreamed of.

Two twentysomething students, Alex and Zoe, are lovers. When Zoe's old boyfriend James returns from Europe, Zoe breaks up with Alex and returns to James. But soon Zoe finds out she's pregnant, and it's Alex's baby.

This drama centers on Hank Chinaski, the fictional alter-ego of "Factotum" author Charles Bukowski, who wanders around Los Angeles, CA trying to live off jobs which don't interfere with his primary interest, which is writing. Along the way, he fends off the distractions offered by women, drinking and gambling.

When Hap Anderson, a widowed 83-year-old Minnesota farmer that thinks he's still quite the ladies' man, sells his family farm, he finds himself adrift and staring a short future in the face. Driven by the possibility of showing up with an old flame and impressing his old army buddies, he sets out to attend his 65th WWII reunion in California with his directionless and unreasonably self-confident granddaughter, Ashley. Each with their own issues and agendas, they head west in a dilapidated Winnebago. Encountering oddball tourist attractions and eccentric characters, they find themselves in seemingly impossible situations with only each other for support. As the journey progresses so does their relationship and they begin to understand and appreciate each other as individuals while discovering that being young and being old, aren't all that different.

Hoping to rekindle an old friendship, childhood buddies Ron and Erik set out for a day’s ice-fishing, on the last day of the ice-fishing season. However, they discover that now in adulthood their comradeship is on thin ice, which easily cracks; one man behaves like a child, the other man like a too-grown-up. Imagination and reason divided. With the help of three mysterious women they meet as they travel further on the ice, can Ron and Erik find a way to reconnect, re-unite, and enjoy a new friendship? And more importantly, catch that elusive giant fish, as the ice begins to melt…