Life is a one take proposition. In ONE TAKE, Kevin never stopped loving Jessie even though she left him years ago and is reported to be dead. When Kevin, out-of-the-blue, receives a card in the mail - an old photo of the two of them with a mysterious message - he is spurred on to discover who sent it and the truth behind Jessie, both past and present.Kevin is suspicious that she might still be alive though this means everyone he meets including Jessie's brother, Jerry, is lying to him. As he tracks down old friends and family, Kevin carries on a running conversation with an imagined Jessie. Just as he is coming to terms with the fact that some questions will remain forever unanswered, he uncovers a shattering truth the will forever change his take on life, love, and sacrafice.

While celebrating their reconciliation and six years of marriage, American actress Sally Nash and British novelist Joe Therrian receive their close friends, some colleagues and their next door neighbors in a party. Under the effect of Ecstasy, revelations are disclosed and relationships deteriorate among the group.