During a sun-soaked Sicilian summer, aimless filmmaking undergrad and back-seat radical Tanino has a fling with Sally, a dreamy American tourist from an upper background. When summer ends, Sally flies back home, without ever reaching out. Clueless, a smitten Tanino decides to pay her a surprise visit under the pretense of returning a camera she left behind. But when he gets there, he quickly realizes the reality of America—and his relationship with Sally's—is far from the idealized version his small-town boy imagination conjured.

This psychedelic tour of life after death is seen entirely from the point of view of Oscar, a young American drug dealer and addict living in Tokyo with his prostitute sister, Linda. When Oscar is killed by police during a bust gone bad, his spirit journeys from the past -- where he sees his parents before their deaths -- to the present -- where he witnesses his own autopsy -- and then to the future, where he looks out for his sister from beyond the grave.