A Retrovirus, which was conceived as a tool for industrial genetic engineering, has gotten out of control and is spreading rapidly. While it crosses all organisms within our ecological system completely indiscriminately (mixing plant with animal and humans) most plants prove more resistant because of their complex DNA. However, the simple genes of the plants lead humans to become grotesque mutations, in most cases even to death. Within one week, 90% of mankind are either extinct or no longer human. However, a small fraction of the earth?s population remains immune to the virus and must survive in this new and constantly changing ecological system. Tom cellar is one the survivors and on an old military base in the Eifel he has entrenched himself. Further survivors come together and succeed in carving out a life in this new world. But the GMOs - the ?genetically modified organisms? - constantly develop themselves further, and soon the fence of the base offers no more protection.

Edward Wilson, the only witness to his father's suicide and member of the Skull and Bones Society while a student at Yale, is a morally upright young man who values honor and discretion, qualities that help him to be recruited for a career in the newly founded OSS. His dedication to his work does not come without a price though, leading him to sacrifice his ideals and eventually his family.