A beautiful workaholic is fired from her job as a marketing executive for a children's toy company. With her life spinning out of control she teams up with her neighbour, who owns a sex shop, to design and promote better sex toys.

Jung-Woo (Kim Sung-Su) is a neurosurgeon and also works in bioengineering research. He is married, but has an ongoing relationship with Yoo-Gyeong (Han Go-Eun). She is a doctor and stands by Jung-Woo. Yoo-Gyeong has a mysterious accident one day and her hand is cut off in the accident. Thanks to Jung-Woo's quick thinking, her hand is reattached successfully with surgery. Yoo-Gyeong's health improves after the surgery, but bizarre events take place around her constantly.

Yeong-cheol is a totally incompetent man in his 40s. He runs a small chicken restaurant, but his fried chicken is the worst-tasting chicken in his village. He loses all his money, which is actually a paltry amount, in the stock market and leads a pathetic life. Worse, he gets bitten by a zombie and becomes one. One day, his family is plunged into a serious crisis because of the money that Yeong-cheol borrows from loan sharks. Yeong-cheol, who sees himself as totally powerless, fights them to save his family.

Soo-min, a bookstore owner entering menopause; Eun-young, a homemaker already in the midst of it; and Hyun, a corporate manager who has not yet experienced it — each faces her own struggles, from work and love to changing bodies and fading confidence. And just when life feels overwhelming… even their friendship begins to fall apart. Can they ever return to the way they once were?

When Joong-pil, the biggest bully in his high-school by far finds himself harboring feelings for a classmate, his entire identity is thrown off balance. Suddenly his smoking, his drinking, his constant swearing and his habit of pushing underclassmen into walls don't seem like good habits anymore. Without his nastiness, who is he? He might just like this girl enough to find out, if he can figure out how.