In 1981 New York City, a collection of twentysomethings try to cope with relationships, loneliness, desire and their individual neuroses on New Years Eve.

After leaving a doctor visit with the worst news, Valerie Dreyfuss and her sister Melissa come to a stop on a lonely stretch of road. Their car is engulfed by a blinding light....12 hours later Valerie wakes to the horror that her sister is gone, nowhere to be found.

A young woman pretends to be pregnant in order to avoid being fired from her job. When that gets her a bunch of special treatment by everyone involved in her life, she tries to keep up the lie for nine months.

The career of a disillusioned producer, who is desperate for a hit, is endangered when his star walks off the film set. Forced to think fast, the producer decides to digitally create an actress "Simone" to sub for the star — the first totally believable synthetic actress.

A woman celebrates her 40th birthday by having her three best friends come and stay with her and her husband for a long weekend. This woman has been in a wheelchair for the past two years, and it has led her to isolate herself inside of her home. Her husband stands by her as he lives with the guilt of causing the car accident which put her in the wheelchair. Over the course of the three day celebration, it is revealed that everyone is struggling with their own lives and identities. When one best friend makes a terrible mistake and betrays the woman on her birthday, everyone is immediately and uncomfortably forced into looking at their own lives and their own limitations.

A prim and proper schoolgirl goes against her society grandmother's wishes when she dates a motorcycle-riding juvenile delinquent.

A television producer with a penchant for drinking and gambling is sent to Las Vegas to convince his troubled niece to enter rehab.

A Navajo shaman is the prime suspect in a murder case in this drama from PBS. But as Officer Jim Chee investigates the case he discovers some unusual events that perplex the veteran lawman, leading to an intriguing climax.