Choreographer Bob Connolly and prolific screenwriter Crane Wilbur teamed up on the direction of Warner Bros.' The Patient in Room 18. Patric Knowles delivers a delightfully comic performance as Lance, an outwardly normal young man obsessed with detective stories. When his obsession threatens to lapse over into lunacy, Lance is sent to the hospital for a nice long rest. It isn't long before he gets mixed up in a genuine murder mystery, using his second-hand knowhow to solve the case. Up-and-coming Ann Sheridan is quite amusing as Lance's nurse and confidante, while the murderer is played by a fellow who is usually cast as the murder victim.

When a banker is found shot dead with a gun in his hand, his daughter refuses to believe it is a suicide. With the help of a detective, she hopes to get to the bottom of the case.

Former bootlegger Remy Marco has a slight problem with foreclosing bankers, a prospective son-in-law, and four hard-to-explain corpses.

When a rival newspaper publisher complains to his captain about possible collusion between himself and reporter Torchy Blane on scooping her rivals in crime news reporting, Det. Lt. Steve McBride determines to thwart her efforts to get inside information - and she determines to go on getting it, by whatever means necessary.