The body of a young Mexican woman is found in the Main Valley, south of Würzburg. Inspector Peter Haller and his colleague Birgit Sacher are involved in solving the crime. Haller is not yet forty and was born in Würzburg. He has a quiet love for his city, for its clarity and familiarity. He will never fully understand how people can become criminals in such a beautiful environment. This is the secret drive behind his investigations, in which he is not just concerned with solving the case, but with looking into the soul of the perpetrator.

Miriam Maertens falls ill with cystic fibrosis and struggles quietly with the disease. Mastering a double life she falls in love and achieves her professional goals. When Miriam gets pregnant, everyone is shocked. When her lungs malfunction, it is a race against time to find a suitable donor.

Development aid worker Carina Nowak walks into a trap set by the Taliban, together with a squadron of German army soldiers. Only she and young soldier Luca survive and they both have to fight to reach their own goals.

After years Michael meets the former school bully Niko and invites him to his home.

For over 15 years, Eve, Estelle, Caroline, Kiki and Judith have been eating every first Tuesday of every month. But that's just the end: Kiki wants to turn an old village school into an idyllic bed and breakfast near a picturesque lake. But the dream threatens to become a nightmare. But even the girlfriends who come to the rescue, have their own problems. Eva is in a midlife crisis, the lawyer Caroline feels persecuted by a dangerous stalker pursued a controversial litigation; and the casual liverwoman Estelle is to be ousted from her company and foundation.

Desperate to keep custody of his daughter, a mixed martial arts fighter abandons a big match and races across Berlin to attend her birthday party.

Police officer Lena Jörning is confronted with the first corpse of her professional career and recognizes her sister, whom she has not heard from for 12 years. The case raises many questions: When did Evelyn return? What roles do Evelyn's husband Claas and Lena's fiancé Bruno play in the death? The criminal investigation team arrives to take over the case. The investigation becomes a dramatic journey into the past for everyone involved, which - until then unrecognizable to Lena - overshadows even the present of the entire village.

Helene is forced by her wicked stepmother Gertrud to do works impossible to done. When she builds a castle for her with the help of the fairy Cleo, there is only room for Helene, in the cellar. One day, Prince Lassmann ride near the castle.

Elke is shocked: yesterday her sister Christa was looking after her kids, today she is dead. Suicide! And the nightmare is only just beginning: Christa leaves behind horrendous debts and a junk property that she financed with overpriced interest on a loan. The family's lawyer suspects that a real estate shark is in collusion with the bank and begins to investigate.

Sophie is admitted to hospital with a fainting spell. She has recently started feeling sick all the time and has a headache. She fears she might be pregnant again. And now she is diagnosed with a brain tumor. Her husband Joachim is never around and their three sons consume all her energy. She throws herself into an affair with the doctor Paul Wolff in order to feel alive again.