In the Fabulous Thirties, Doc Savage and his five Amazing Adventurers are sucked into the mystery of Doc's father disappearing in the wilds of South America. The maniacal Captain Seas tries to thwart them at every turn as they travel to the country of Hidalgo to investigate Doc's father's death and uncover a vast horde of Incan gold.

Carrie, Mitzie, and Chicago get in trouble a lot in the women's prison, but are offered early parolement if they agree to become subjects of a study on human aggression and antisocial behavior at a Kansas City college. Dr. Blalock, the professor in charge of the study, is accepting money under the table from a shady government contact to use an experimental drug on the women. The drug induces the same hostile behavior the doctor is supposedly trying to cure, and after a while the women have a hard time conducting themselves in a civil manner.

A story about the rich McCulloch Family, their overbearing father and the children's misguided blaming him for everything that doesn't go right.

Uncle Frank Kelly calls on Harry Crown to help him in a gang war. The war becomes personal when Harry's new girlfriend is kidnapped by Uncle Frank's enemy, Big Eddie.