Alex Tallman has never hurt another human being. As a nurse she has dedicated her life to the care of others...until one shattering night her whole life changes forever. Three strangers brutally beat and rape Alex. She is abandoned naked. A victim no more, she pursues her assailants relentlessly. At a firing range she designs her revenge for her targets in a tight pattern of 45 mm. slugs to the groin. At night she stalks her tormentors and returns in kind the terror they inflicted upon her.

Bill is a penniless drifter who scams strangers out of just enough money to feed himself and his partner in crime, an orphan girl known as Curly Sue. Bill and Curly Sue target Grey, a yuppie lawyer, but their con takes an unexpected turn when the successful woman begins to like the ramshackle duo. But there's one problem—Grey's jealous, conniving boyfriend, Walker.

New York's toughest lady detectives re-team to solve the murder of a homeless transient who had been terrorizing the residents of a posh apartment building with screaming threats, insults and physical intimidation. Though the cops think the culprit is another street person, Cagney and Lacey believe the real killer is one of the tenants, many of whom have ample reason to have murdered the boorish bum.