This is not a film about gun control. It is a film about the fearful heart and soul of the United States, and the 280 million Americans lucky enough to have the right to a constitutionally protected Uzi. From a look at the Columbine High School security camera tapes to the home of Oscar-winning NRA President Charlton Heston, from a young man who makes homemade napalm with The Anarchist's Cookbook to the murder of a six-year-old girl by another six-year-old. Bowling for Columbine is a journey through the US, through our past, hoping to discover why our pursuit of happiness is so riddled with violence.

Set both in Latin America and the United States, the film explores the historic and current relationship of Washington with countries such as Venezuela, Bolivia and Chile. Pilger says that the film "...tells a universal story... analysing and revealing, through vivid testimony, the story of great power behind its venerable myths. It allows us to understand the true nature of the so-called "war on terror". According to Pilger, the film’s message is that the greed and power of empire is not invincible and that people power is always the "seed beneath the snow".

Before his journey into exile Jacobo Arbenz, the overthrown President of Guatemala, is presented to photographers stripped down to his underwear: an image seen around the world. Arbenz had led the successful 1944 revolt against the military dictatorship, a regime that had oppressed Guatemala since colonialism. Arbenz, the son of Swiss immigrants, was celebrated as a national hero. Elected President in 1950, Arbenz was not a member of any party - he didn't issue any manifestos. But he began to fulfill his promises - farmers got their own land. 'The first act of justice since colonial times,' said Arbenz. In the early 1950s, with the Cold War intensifying, then Vice President Richard Nixon said, 'Arbenz is not a Guatemalan President.' Nixon called him 'a foreigner, manipulated by foreign powers.' The young President of Guatemala was soon overthrown, declared a traitor, and chased out of the country.

Ernesto "Che" Guevara's controversial story told by the Mexican writer Paco Ignacio Taibo II. He revisits places where the guerrilla and revolutionary leader has passed and interviews people who knew Che, making revelations about this important figure in Cuba's political history.

Tehran, Iran, August 19, 1953. A group of Iranian conspirators who, with the approval of the deposed tyrant Mohammad Reza Pahlavi, have conspired with agents of the British MI6 and the US CIA, manage to put an end to the democratic government led by Mohammad Mosaddegh, a dramatic event that will begin the tragic era of coups d'état that, orchestrated by the CIA, will take place, over the following decades, in dozens of countries around the world.