The Wandering Jew tells the story of Arthur Levi (Jacob Ben-Ami), a German-Jewish artist who experiences the new German antisemitism when his masterpiece, a portrait of his Polish-born father entitled "The Eternal Wanderer" is rejected by the Berlin Academy of Art, which also asks his resignation as professor. Later in the film the figure in the painting comes to life and tells Levi the story of the persecution of the Jewish people. The film ends with footage of an anti-Hitler rally at New York City's Madison Square Garden and Levi's resolve to bear onward in the face of adversity.

The story of the first colony of immigrants to arrive in the province of Santa Fe, in Argentina.