When Missouri farm boy Jesse James witnesses the lynching of his father by the Yankees, he forsakes his family's homestead to find his brother Frank, a soldier in Quantrill's Raiders, a renegade band of Confederates. Bent on revenge, Jesse begs to join the raiders.

Bikers, Nazis, Mafiosi, and the FBI all clash in this wild and wooly exploitation picture from director Al Adamson. Mark Adams (John Gabriel) is an FBI agent who has been assigned to infiltrate an organized crime ring that has obtained a set of printing plates that will allow them to produce nearly perfect counterfeit 20-dollar bills. The plates were made in Germany during World War II, and were discovered by a radical right-wing group hoping to restore the Nazi Party to power. The American gangsters are in cahoots with a group of wealthy American neo-Nazis sympathetic to the new German cause, led by fugitive war criminal Count von Delberg (Kent Taylor); the count has in turn recruited a vicious motorcycle gang, the Bloody Devils, to do his dirty work.

Ex-con Joseph Braden has his car temporarily stolen by a pair of bank robbers who hide their loot in the vehicle's spare tire. After the car is repossessed, it's sold to the kindly Rev. Daniel Sheridan, who immediately sets out on a fishing trip. Not knowing that his new automobile was recently used in a heist, Father Dan gets the surprise of his life when he's suddenly stopped by a police officer.

A policeman is accused of manslaughtering a 14-year-old boy but is acquitted of all charges. Still, he feels a lot of guilt and begins to doubt if he really is innocent after all.