Lepke is the feared leader of "Murder Incorporated" in this underworld drama based on the life of Louis "Lepke" Buchalter. Lepke began his criminal career as a petty thief in his teens; a stretch in prison taught him the finer points of life on the wrong side of the law. After getting out of jail, Lepke and his pal Gurrah Shapiro join a gang who hire themselves out as strikebreakers, and the vicious but clever Lepke soon rises through the ranks.

Young Al Capone catches the eye of Johnny Torrio, a criminal visiting New York from Chicago. Torrio invites Capone to move to Illinois to help run his Prohibition-era alcohol sales operation. Capone rises through the ranks of Torrio's gang and eventually takes over. On top, he works to consolidate his power by eliminating his enemies, fixing elections to his advantage and getting rich. In his spare time, Capone courts the principled Iris Crawford.

Cosmo Vittelli, the proprietor of a sleazy, low-rent Hollywood cabaret, has a real affection for the women who strip in his peepshows and the staff who keep up his dingy establishment. He also has a major gambling problem that has gotten him in trouble before. When Cosmo loses big-time at an underground casino run by mobster Mort, he isn't able to pay up. Mort then offers Cosmo the chance to pay back his debt by knocking off a pesky, Mafia-protected bookie.

The relationship between Lelia, a light-skinned black woman, and Tony, a white man is put in jeopardy when Tony meets Lelia’s darker-skinned jazz singer brother, Hugh, and discovers that her racial heritage is not what he thought it was.

After serving 12 years behind bars for armed robbery, tough guy Hank McCain finds himself the pawn of a ruthless mob runt's rebellion against a high level don. When McCain discovers that he's been betrayed and abandoned by his new employer, he retaliates with a high stakes Las Vegas casino heist that erupts into all-out war on the streets of Los Angeles, San Francisco and New York. Neither blood, nor lust, nor wedding vows can come between McCain and his money ... or his machine gun.